Publications

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Our work is published in leading journals spanning analytical chemistry, nanotechnology, pharmaceutics, and biomedical sciences. We focus on advancing mass spectrometry imaging and next-generation drug delivery systems, with applications in oncology, dermatology, and central nervous system therapeutics.

2026

Abu Ghoush, R.; Geday, F.; Alon, O.; Kanchustambham, V.L.; Noll, S.E.; Margulis, K.

Imaging mammalia lipids using desorption electrospray ionization mass spectrometry.

Analytica Chimica Acta. 2026, v olume 1392, 345143.

2025

Yakobi-Arancibia, R.; Bentov-Arava, E.; Morshin, A.; Elia, J.; Natsheh, H.; Levi-Kalisman, Y.; Ushki, R; Elia, A.; Touitou, E.; Margulis, K.

A Rapid Assessment Approach for Skin Stratum-Targeted Drug Delivery Systems Using Mass Spectrometry Imaging and Spatial Clustering.

Small Sci. 2025, 5, 2500061.

Rajs, N.; Harush-Brosh,Y.; Raisch, R.; Yakobi, R.; Zoabi, A.; Golan, G.N.; Shpitzen, M.; Wiesner, S.; Elad, M.L.; Kaplan, T.; Margulis, K.

Determining Time Since Deposition of Latent Fingerprints on Forensic Adhesive Tape Using Ultrafast DESI-MS and Machine Learning.

Scientific Reports 2025, 15:18413.

Sultan, A.; Zoabi, A.; Morshin,A.; Shalev, O.; Lazarovici, P.; Margulis, K.

Antitumor Activity of Alexidine Dihydrochloride Nanocarriers in Renal Cell Carcinoma.

Mol. Pharmaceutics 2025, 22, 6014−6024.

2024

Zoabi, A.; Sultan, A.; Abo Alhija, M.; Remennik, S.; Radko, A.; Margulis, K.

Stereoselective Interactions of Chiral Polyurea Nanocapsules with Albumins.

ACS Appl. Mater. Interfaces 2024, 16, 58168−58179.

Messer, L.; Zoabi, A.; Yakobi, R.; Natsheh, H.; Touitou, E.; Margulis, K.

Evaluation of nasal delivery systems of olanzapine by desorption electrospray ionization mass spectrometry imaging.

International Journal of Pharmaceutics 2024, 650, 123664.

Zoabi, A.; Bentov-Arava, E.; Sultan, A.; Elia, A.; Shalev, O.; Orevi, M.; Gofrit, O. N., Margulis, K.

Adipose tissue composition determines its computed tomography radiodensity .

European Radiology 2024, 34:1635–1644.

2023

Soudah, T.; Zoabi, A.; Margulis, K.

Desorption Electrospray Ionization Mass Spectrometry Imaging In Discovery And Development Of Novel Therapies.

Mass Spectrometry Reviews 2023, 42(2):751-778.

2022

Gouw, A. M; Kumar, V.; Resendez, A.; Alvina, F.B.; Liu, N.S.; Margulis, K.; Tong, L.; Zare, R.N.; Malhotra, S.V.; Felsher, D.W.

Azapodophyllotoxin Causes Lymphoma and Kidney Cancer Regression by Disrupting Tubulin and Monoglycerols.

ACS Med Chem Letters Journal 2022, 13(4):615–622.

Armstrong, N.; Storey, C.M.; Noll, S.E.; Margulis, K.; Soe, M.H.; Xu, H.; Yeh, B.; Fishbein, L.; Kebebew, E.; Howitt, B.E.; Zare, R.N.; Sage, J.; Annes, J.P.

SDHB knockout and succinate accumulation are insufficient for tumorigenesis but dual SDHB/NF1 loss yields SDHx-like pheochromocytomas.

Cell Rep. 2022, 1;38(9):110453.

2021

Zoabi, A.; Touitou, E.; Margulis, K.

Recent Advances In Nanomaterials For Dermal And Transdermal Applications.

Colloids And Interfaces, 2021, 5, 1, Pp. 18.

Zoabi, A.; Margulis, K.

Differential Interactions Of Chiral Nanocapsules With DNA.

International Journal Of Molecular Sciences, 2021, 22, 2, Pp. 584.

2020

Margulis, K.; Honkala, A.; Kalashnikova, I.; Noll, S.E.; Hill, M.; Zare, R.N.; Smith, B.R.

Nanoparticles Decorated with Granulocyte-Colony Stimulating Factor for Targeting Myeloid Cells.

Nanoscale, 2020, 12, 4, Pp. 2752–2763.

Selected Earlier Publications (2009–2019)

Multiple peer-reviewed articles in ACS Nano, PNAS, Analytical Chemistry, Nanoscale, Journal of Pharmaceutical Sciences, and others covering nanocarriers, DESI-MSI imaging, drug delivery systems, and biomedical nanotechnology.